Then under the Adobe PDF Settings tab click on DEFAULT, HIGH QUALITY PRINT. Click on START, DEVICES & PRINTERS, ADOBE PRINTER, PRINTER PROPERTIES, PREFERENCES. I was having a similar problem and the following fixed it for me (I'm using a Windows 7 Platform and Office 2010 Professional and was attempting to print a MapPoint Map to Adobe PDF in Adobe X.): It sounds like Adobe is attempting to use its default fonts instead of the document's fonts. The following procedure, discovered by a Part III student, fixed this on MCS Windows and is worth trying if you have similar problems printing from other Windows machines. 
This is due to Adobe trying to re-create the document using its own fonts instead of the document's fonts.
Sometimes a PDF file looks fine on screen but it prints in an unsightly substitute font which impedes reading, or symbols are replaced by small rectangles.
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